HRID945807

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID8028

Tetrahydrofuran

C4H8O

HCID15908

1-Ethyl-3-(3'-dimethylaminopropyl)carbodiimide

C8H17N3

HCID75771

1-Hydroxybenzotriazole

C6H5N3O

HCID81531

Diisopropylethylamine

C8H19N

HCID21867017

O-[2-(Ethenyloxy)ethyl]hydroxylamine

C4H9NO2

结构：O=C(O)c1ccn2cncc2c1Nc1ccc(C2CCC2)cc1F

HCID59565203

未命名化合物

PRODUCTS

生成物

结构：C=COCCONC(=O)c1ccn2cncc2c1Nc1ccc(C2CCC2)cc1F

HCID59565189

未命名化合物

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-7fa7d412d9f94090b059087d08989b45
来源数据集: Validation data from https://doi.org/10.1039/C8SC04228D
DOI: 10.1039/C8SC04228D
来源说明: Validation data from https://doi.org/10.1039/C8SC04228D

反应 SMILES

[CH2:62]1[O:63][CH2:64][CH2:65][CH2:66]1.[CH3:25][CH2:26][N:27]=[C:28]=[N:29][CH2:30][CH2:31][CH2:32][N:33]([CH3:34])[CH3:35].[CH:1]1([c:5]2[cH:6][c:7]([F:24])[c:8]([NH:11][c:12]3[c:13]4[n:14]([cH:15][cH:16][c:17]3[C:18](=[O:19])[OH:20])[cH:21][n:22][cH:23]4)[cH:9][cH:10]2)[CH2:2][CH2:3][CH2:4]1.[CH:46]([N:47]([CH2:48][CH3:49])[CH:50]([CH3:51])[CH3:52])([CH3:53])[CH3:54].[CH:55](=[CH2:56])[O:57][CH2:58][CH2:59][O:60][NH2:61].[OH:36][n:37]1[c:38]2[c:39]([cH:40][cH:41][cH:42][cH:43]2)[n:44][n:45]1>>[CH:1]1([c:5]2[cH:6][c:7]([F:24])[c:8]([NH:11][c:12]3[c:13]4[n:14]([cH:15][cH:16][c:17]3[C:18](=[O:20])[NH:61][O:60][CH2:59][CH2:58][O:57][CH:55]=[CH2:56])[cH:21][n:22][cH:23]4)[cH:9][cH:10]2)[CH2:2][CH2:3][CH2:4]1