HRID94668

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID2155

2-Aminothiazole

C3H4N2S

HCID8028

Tetrahydrofuran

C4H8O

HCID8454

N-Methylpyrrolidine

C5H11N

结构：C=C(C)OC(=O)NC(Cc1ccccc1)(c1ccc(F)cc1)c1cc(F)cc(OC(F)(F)C(F)F)c1

HCID72290899

未命名化合物

PRODUCTS

生成物

结构：O=C(Nc1nccs1)NC(Cc1ccccc1)(c1ccc(F)cc1)c1cc(F)cc(OC(F)(F)C(F)F)c1

HCID74065125

未命名化合物

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-6346527aac20401ea5dbd65c6f236d2f
来源数据集: Training data from https://doi.org/10.1039/C8SC04228D (2/10)
DOI: 10.1039/C8SC04228D
来源说明: Training data from https://doi.org/10.1039/C8SC04228D (2/10)

反应 SMILES

[CH2:49]1[O:50][CH2:51][CH2:52][CH2:53]1.[CH3:43][N:44]1[CH2:45][CH2:46][CH2:47][CH2:48]1.[F:1][c:2]1[cH:3][c:4]([C:15]([CH2:16][c:17]2[cH:18][cH:19][cH:20][cH:21][cH:22]2)([c:23]2[cH:24][cH:25][c:26]([F:29])[cH:27][cH:28]2)[NH:30][C:31]([O:32][C:34]([CH3:35])=[CH2:36])=[O:33])[cH:5][c:6]([O:8][C:9]([CH:10]([F:11])[F:12])([F:13])[F:14])[cH:7]1.[NH2:37][c:38]1[s:39][cH:40][cH:41][n:42]1>>[F:1][c:2]1[cH:3][c:4]([C:15]([CH2:16][c:17]2[cH:18][cH:19][cH:20][cH:21][cH:22]2)([c:23]2[cH:24][cH:25][c:26]([F:29])[cH:27][cH:28]2)[NH:30][C:31](=[O:32])[NH:37][c:38]2[s:39][cH:40][cH:41][n:42]2)[cH:5][c:6]([O:8][C:9]([CH:10]([F:11])[F:12])([F:13])[F:14])[cH:7]1