Benzoic Acid → 4-(3,4,5-Trifluorophenyl)aminotetrahydropyran
Reaction equation
[BH4-:28].[F:1][c:2]1[cH:3][c:4]([NH2:5])[cH:6][c:7]([F:10])[c:8]1[F:9].[Na+:29].[Na:27].[O:11]1[CH2:12][CH2:13][C:14](=[O:17])[CH2:15][CH2:16]1.[OH:18][C:19]([c:20]1[cH:21][cH:22][cH:23][cH:24][cH:25]1)=[O:26]>>[F:1][c:2]1[cH:3][c:4]([NH:5][CH:14]2[CH2:13][CH2:12][O:11][CH2:16][CH2:15]2)[cH:6][c:7]([F:10])[c:8]1[F:9]Participants
7
Sources & evidence
- ORD record
- ord-2bed0f4f334340d3be4180651bf2af11
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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