Ammonium → 2-(4-Chlorobenzyl)-2-ethyl-1-(3-pyridyl)-1-butanol

HRID 950096Notes

Reaction equation

HRID 950096 reaction equation
[Br:1][c:2]1[cH:3][n:4][cH:5][cH:6][cH:7]1.[CH2:8]([Li:9])[CH2:10][CH2:11][CH3:12].[CH3:13][CH2:14][CH2:15][CH2:16][CH2:17][CH3:18].[CH3:37][CH2:38][O:39][CH2:40][CH3:41].[Cl-:34].[Cl:19][c:20]1[cH:21][cH:22][c:23]([CH2:24][C:25]([CH:26]=[O:27])([CH2:28][CH3:29])[CH2:30][CH3:31])[cH:32][cH:33]1.[ClH:36].[NH4+:35]>>[c:2]1([CH:26]([C:25]([CH2:24][c:23]2[cH:22][cH:21][c:20]([Cl:19])[cH:33][cH:32]2)([CH2:28][CH3:29])[CH2:30][CH3:31])[OH:27])[cH:3][n:4][cH:5][cH:6][cH:7]1

Participants

9

Reactant 8

HCID 223AmmoniumHCID 312ChlorideHCID 313Hydrochloric AcidHCID 3283Diethyl EtherHCID 8058HexaneHCID 122863-BromopyridineHCID 151008312-(4-Chlorobenzyl)-2-ethylbutanalHCID 178418339Butyllithium

Product 1

HCID 151008322-(4-Chlorobenzyl)-2-ethyl-1-(3-pyridyl)-1-butanol

Sources & evidence

ORD record
ord-adadbc07dc5f43ee987579e2b7287a68
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

Loading…