3-Hydroxypyridine → 3-(1-Methyl-3-pyrrolidinyloxy)-pyridine

HRID 950497Notes

Reaction equation

HRID 950497 reaction equation
[CH2:46]1[O:47][CH2:48][CH2:49][CH2:50]1.[CH3:32][N:33]1[CH2:34][CH:35]([OH:38])[CH2:36][CH2:37]1.[O:20]=[C:21]([O:22][CH2:23][CH3:24])[N:25]=[N:26][C:27]([O:28][CH2:29][CH3:30])=[O:31].[OH:39][c:40]1[cH:41][n:42][cH:43][cH:44][cH:45]1.[c:1]1([P:2]([c:3]2[cH:4][cH:5][cH:6][cH:7][cH:8]2)[c:9]2[cH:10][cH:11][cH:12][cH:13][cH:14]2)[cH:15][cH:16][cH:17][cH:18][cH:19]1>>[CH3:32][N:33]1[CH2:34][CH:35]([O:38][c:40]2[cH:41][n:42][cH:43][cH:44][cH:45]2)[CH2:36][CH2:37]1

Participants

6

Reactant 5

HCID 79713-HydroxypyridineHCID 8028TetrahydrofuranHCID 11776TriphenylphosphineHCID 930741-Methyl-3-pyrrolidinolHCID 220568ethyl N-ethoxycarbonyliminocarbamate

Product 1

HCID 101302113-(1-Methyl-3-pyrrolidinyloxy)-pyridine

Sources & evidence

ORD record
ord-9442c78bb7d24b05820acf11baa312c5
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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