Sodium ion → 1-(Tert-butyloxycarbonyl)-4-(4-ethoxyphenyl)piperazine

HRID 950754Notes

Reaction equation

HRID 950754 reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH2:10][N:11]([c:14]2[cH:15][cH:16][c:17]([OH:20])[cH:18][cH:19]2)[CH2:12][CH2:13]1.[CH2:28]([CH3:29])[I:30].[CH2:31]1[O:32][CH2:33][CH2:34][CH2:35]1.[H-:21].[Na+:22].[O:23]=[CH:24][N:25]([CH3:26])[CH3:27]>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH2:10][N:11]([c:14]2[cH:15][cH:16][c:17]([O:20][CH2:28][CH3:29])[cH:18][cH:19]2)[CH2:12][CH2:13]1

Participants

7

Reactant 6

HCID 923Sodium ionHCID 6228DimethylformamideHCID 6340IodoethaneHCID 8028TetrahydrofuranHCID 166653HydrideHCID 116877404-(4-Hydroxy-phenyl)-piperazine-1-carboxylic acid tert-butyl ester

Product 1

HCID 232888571-(Tert-butyloxycarbonyl)-4-(4-ethoxyphenyl)piperazine

Sources & evidence

ORD record
ord-2d4d8fec335640d9948d2e87a5f48c37
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

Loading…