Tetrahydrofuran → 2-((2-(6-Amino-3,4-dihydroquinolin-1(2H)-yl)ethyl)(methyl)amino)ethanol
Reaction equation
[Br:20][c:21]1[cH:22][c:23]2[c:28]([cH:29][cH:30]1)[N:27]([CH2:31][CH2:32][N:33]([CH2:34][CH2:35][OH:36])[CH3:37])[CH2:26][CH2:25][CH2:24]2.[C:1]([P:2]([C:3]([CH3:4])([CH3:5])[CH3:6])[C:7]([CH3:8])([CH3:9])[CH3:10])([CH3:11])([CH3:12])[CH3:13].[CH2:48]1[O:49][CH2:50][CH2:51][CH2:52]1.[CH3:14][CH2:15][CH2:16][CH2:17][CH2:18][CH3:19].[CH3:38][Si:39]([N-:42][Si:40]([CH3:41])([CH3:43])[CH3:44])([CH3:45])[CH3:46].[Li+:47].[O:55]=[C:56]([CH:57]=[CH:58][c:59]1[cH:60][cH:61][cH:62][cH:63][cH:64]1)[CH:65]=[CH:66][c:67]1[cH:68][cH:69][cH:70][cH:71][cH:72]1.[O:73]=[C:74]([CH:75]=[CH:76][c:77]1[cH:78][cH:79][cH:80][cH:81][cH:82]1)[CH:83]=[CH:84][c:85]1[cH:86][cH:87][cH:88][cH:89][cH:90]1.[O:91]=[C:92]([CH:93]=[CH:94][c:95]1[cH:96][cH:97][cH:98][cH:99][cH:100]1)[CH:101]=[CH:102][c:103]1[cH:104][cH:105][cH:106][cH:107][cH:108]1.[Pd:53].[Pd:54]>>[c:21]1([NH2:42])[cH:22][c:23]2[c:28]([cH:29][cH:30]1)[N:27]([CH2:31][CH2:32][N:33]([CH2:34][CH2:35][OH:36])[CH3:37])[CH2:26][CH2:25][CH2:24]2Participants
9
Reactant 8
Product 1
Sources & evidence
- ORD record
- ord-498b8b3d41d24d4ab09748b931536ea1
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (2/10)
Reaction notes
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