Pyridine → N-Isopropyl-4-fluoro-2-nitroaniline

HRID 951649Notes

Reaction equation

HRID 951649 reaction equation
[BH3:26].[CH3:12][O:13][C:14]([CH3:15])([CH3:16])[O:17][CH3:18].[CH3:27][c:28]1[cH:29][cH:30][cH:31][cH:32][cH:33]1.[CH3:40][CH2:41][O:42][C:43]([CH3:44])=[O:45].[CH3:46][CH2:47][CH2:48][CH2:49][CH2:50][CH3:51].[F:1][c:2]1[cH:3][c:4]([N+:9](=[O:10])[O-:11])[c:5]([NH2:6])[cH:7][cH:8]1.[OH:19][C:20]([C:21]([F:22])([F:23])[F:24])=[O:25].[cH:34]1[cH:35][cH:36][n:37][cH:38][cH:39]1>>[F:1][c:2]1[cH:3][c:4]([N+:9](=[O:10])[O-:11])[c:5]([NH:6][CH:14]([CH3:15])[CH3:16])[cH:7][cH:8]1

Participants

9

Reactant 8

HCID 1049PyridineHCID 1140TolueneHCID 6331BoraneHCID 6422Trifluoroacetic acidHCID 64952,2-DimethoxypropaneHCID 8058HexaneHCID 8857Ethyl AcetateHCID 677694-Fluoro-2-nitroaniline

Product 1

HCID 2775219N-Isopropyl-4-fluoro-2-nitroaniline

Sources & evidence

ORD record
ord-cd93a915b4aa4065be94b03887719fa4
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

Loading…