Dimethylformamide → Sorafenib

HRID 951669Notes

Reaction equation

[CH3:53][CH2:54][O:55][C:56](=[O:57])[CH3:58].[CH:48]([N:49]([CH3:50])[CH3:51])=[O:52].[Cl:1][C:2]([C:3](=[O:4])[NH:5][c:6]1[cH:7][c:8]([C:13]([F:14])([F:15])[F:16])[c:9]([Cl:12])[cH:10][cH:11]1)([Cl:17])[Cl:18].[N:19]12[CH2:20][CH2:21][CH2:22][N:23]=[C:24]1[CH2:25][CH2:26][CH2:27][CH2:28][CH2:29]2.[NH2:30][c:31]1[cH:32][cH:33][c:34]([O:35][c:36]2[cH:37][c:38]([C:42](=[O:43])[NH:44][CH3:45])[n:39][cH:40][cH:41]2)[cH:46][cH:47]1>>[C:3](=[O:4])([NH:5][c:6]1[cH:7][c:8]([C:13]([F:14])([F:15])[F:16])[c:9]([Cl:12])[cH:10][cH:11]1)[NH:30][c:31]1[cH:32][cH:33][c:34]([O:35][c:36]2[cH:37][c:38]([C:42](=[O:43])[NH:44][CH3:45])[n:39][cH:40][cH:41]2)[cH:46][cH:47]1