2,4-Dihydroxybenzaldehyde → 2-Hydroxy-4-[2-(5-methyl-2-phenyl-oxazol-4-yl)-ethoxy]-benzaldehyde

HRID 951943Notes

Reaction equation

HRID 951943 reaction equation
[CH2:61]1[O:62][CH2:63][CH2:64][CH2:65]1.[N:45]([C:46]([O:47][C:48]([CH3:49])([CH3:50])[CH3:51])=[O:52])=[N:53][C:54]([O:55][C:56]([CH3:57])([CH3:58])[CH3:59])=[O:60].[OH:1][c:2]1[c:3]([CH:4]=[O:5])[cH:6][cH:7][c:8]([OH:10])[cH:9]1.[c:11]1([P:12]([c:13]2[cH:14][cH:15][cH:16][cH:17][cH:18]2)[c:19]2[cH:20][cH:21][cH:22][cH:23][cH:24]2)[cH:25][cH:26][cH:27][cH:28][cH:29]1.[c:30]1(-[c:36]2[o:37][c:38]([CH3:44])[c:39]([CH2:41][CH2:42][OH:43])[n:40]2)[cH:31][cH:32][cH:33][cH:34][cH:35]1>>[OH:1][c:2]1[c:3]([CH:4]=[O:5])[cH:6][cH:7][c:8]([O:10][CH2:42][CH2:41][c:39]2[c:38]([CH3:44])[o:37][c:36](-[c:30]3[cH:31][cH:32][cH:33][cH:34][cH:35]3)[n:40]2)[cH:9]1

Participants

6

Reactant 5

HCID 72132,4-DihydroxybenzaldehydeHCID 8028TetrahydrofuranHCID 11776TriphenylphosphineHCID 97268Di-tert-butyl azodicarboxylateHCID 7255852-(5-Methyl-2-phenyl-4-oxazolyl)ethanol

Product 1

HCID 222739232-Hydroxy-4-[2-(5-methyl-2-phenyl-oxazol-4-yl)-ethoxy]-benzaldehyde

Sources & evidence

ORD record
ord-e28f751e60ed48d3a61ea27189de79b3
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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