Cyanide → Methyl 5-cyano-2-methoxybenzoate

HRID 951976Notes

Reaction equation

HRID 951976 reaction equation
[Br:1][c:2]1[cH:3][cH:4][c:5]([O:12][CH3:13])[c:6]([C:7](=[O:8])[O:9][CH3:10])[cH:11]1.[C-:19]#[N:20].[C-:22]#[N:23].[CH3:14][N:15]([CH3:16])[CH:17]=[O:18].[Zn+2:21]>>[c:2]1([C:14]#[N:15])[cH:3][cH:4][c:5]([O:12][CH3:13])[c:6]([C:7](=[O:8])[O:9][CH3:10])[cH:11]1

Participants

5

Reactant 4

HCID 5975Cyanide2×HCID 6228DimethylformamideHCID 32051Zinc(2+)HCID 13297188Methyl 5-bromo-2-methoxybenzoate

Product 1

HCID 18464789Methyl 5-cyano-2-methoxybenzoate

Sources & evidence

ORD record
ord-9396ebf7a19b4d95ad23b28a5c1a6550
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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