Water → tert-Butyl 4-{6-[3-(4-fluoro-phenyl)-prop-1-ynyl]-1-methyl-2,4-dioxo-1,4-dihydro-2H-quinazolin-3-ylmethyl}-benzoate

HRID 952045Notes

Reaction equation

[CH:29]([N:30]([CH:31]([CH3:32])[CH3:33])[CH2:34][CH3:35])([CH3:36])[CH3:37].[Cu:54][I:55].[F:38][c:39]1[cH:40][cH:41][c:42]([CH2:45][C:46]#[CH:47])[cH:43][cH:44]1.[I:1][c:2]1[cH:3][c:4]2[c:5](=[O:28])[n:6]([CH2:14][c:15]3[cH:16][cH:17][c:18]([C:19](=[O:20])[O:21][C:22]([CH3:23])([CH3:24])[CH3:25])[cH:26][cH:27]3)[c:7](=[O:13])[n:8]([CH3:12])[c:9]2[cH:10][cH:11]1.[O:49]=[CH:50][N:51]([CH3:52])[CH3:53].[OH2:48]>>[c:2]1([C:47]#[C:46][CH2:45][c:42]2[cH:41][cH:40][c:39]([F:38])[cH:44][cH:43]2)[cH:3][c:4]2[c:5](=[O:28])[n:6]([CH2:14][c:15]3[cH:16][cH:17][c:18]([C:19](=[O:20])[O:21][C:22]([CH3:23])([CH3:24])[CH3:25])[cH:26][cH:27]3)[c:7](=[O:13])[n:8]([CH3:12])[c:9]2[cH:10][cH:11]1