Dimethylformamide → Ethyl 4-(4-benzylbenzamido)-3-fluorobenzoate

HRID 952387Notes

Reaction equation

HRID 952387 reaction equation
[C:17]([Cl:18])(=[O:19])[C:20]([Cl:21])=[O:22].[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[c:8]1[cH:9][cH:10][c:11]([C:12](=[O:13])[OH:14])[cH:15][cH:16]1.[CH3:23][CH2:24][N:25]([CH2:26][CH3:27])[CH2:28][CH3:29].[Cl:43][CH2:44][Cl:45].[NH2:30][c:31]1[c:32]([F:42])[cH:33][c:34]([C:35](=[O:36])[O:37][CH2:38][CH3:39])[cH:40][cH:41]1.[O:46]=[CH:47][N:48]([CH3:49])[CH3:50]>>[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[c:8]1[cH:9][cH:10][c:11]([C:12](=[O:14])[NH:30][c:31]2[c:32]([F:42])[cH:33][c:34]([C:35](=[O:36])[O:37][CH2:38][CH3:39])[cH:40][cH:41]2)[cH:15][cH:16]1

Participants

7

Reactant 6

HCID 6228DimethylformamideHCID 6344DichloromethaneHCID 8471TriethylamineHCID 65578Oxalyl chlorideHCID 1364294-Benzylbenzoic acidHCID 20536493Ethyl 4-amino-3-fluorobenzoate

Product 1

HCID 57625194Ethyl 4-(4-benzylbenzamido)-3-fluorobenzoate

Sources & evidence

ORD record
ord-322ff98b98eb4e9bb6ffca2a984ae58d
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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