Hydrochloric Acid → HCID 59639612, compound

HRID 953442Notes

Reaction equation

HRID 953442 reaction equation
[CH3:45][N:46]1[CH2:47][CH2:48][CH2:49][C:50]1=[O:51].[CH3:52][CH2:53][O:54][C:55]([CH3:56])=[O:57].[CH3:58][CH2:59][O:60][CH2:61][CH3:62].[ClH:32].[F:1][c:2]1[c:3](-[n:9]2[c:10](=[O:31])[cH:11][cH:12][c:13]3[c:14]2[n:15][c:16]([S:27]([CH3:28])(=[O:29])=[O:30])[n:17][c:18]3-[c:19]2[c:20]([CH3:26])[cH:21][c:22]([F:25])[cH:23][cH:24]2)[c:4]([F:8])[cH:5][cH:6][cH:7]1.[K+:39].[K+:40].[NH2:33][CH2:34][C:35](=[O:36])[O:37][CH3:38].[O-:41][C:42]([O-:43])=[O:44]>>[F:1][c:2]1[c:3](-[n:9]2[c:10](=[O:31])[cH:11][cH:12][c:13]3[c:14]2[n:15][c:16]([NH:33][CH2:34][C:35](=[O:36])[O:37][CH3:38])[n:17][c:18]3-[c:19]2[c:20]([CH3:26])[cH:21][c:22]([F:25])[cH:23][cH:24]2)[c:4]([F:8])[cH:5][cH:6][cH:7]1

Participants

9

Reactant 8

HCID 313Hydrochloric AcidHCID 813Potassium Cation2×HCID 3283Diethyl EtherHCID 8857Ethyl AcetateHCID 13387N-methyl-2-pyrrolidoneHCID 19660Carbonate IonHCID 69221Glycine methyl esterHCID 596395548-(2,6-difluoro-phenyl)-4-(4-fluoro-2-methyl-phenyl)-2-methanesulfonyl-8H-pyrido[2,3-d]pyrimidin-7-one

Product 1

HCID 59639612HCID 59639612, compound

Sources & evidence

ORD record
ord-e9f123cb3cb74bf4b7c8da7bc8a73e24
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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