Ammonium → 1-(2-Bromo-thiazol-5-yl)-propan-1-ol

HRID 954737Notes

Reaction equation

HRID 954737 reaction equation
[Br-:9].[Br:1][c:2]1[s:3][c:4]([CH:7]=[O:8])[cH:5][n:6]1.[CH2:10]([CH3:11])[Mg+:12].[CH2:15]1[O:16][CH2:17][CH2:18][CH2:19]1.[CH3:20][CH2:21][O:22][C:23](=[O:24])[CH3:25].[Cl-:13].[NH4+:14]>>[Br:1][c:2]1[s:3][c:4]([CH:7]([OH:8])[CH2:10][CH3:11])[cH:5][n:6]1

Participants

8

Reactant 7

HCID 223AmmoniumHCID 259Bromide ionHCID 312ChlorideHCID 8028TetrahydrofuranHCID 8857Ethyl AcetateHCID 27732592-Bromo-1,3-thiazole-5-carbaldehydeHCID 178461628HCID 178461628, compound

Product 1

HCID 584433781-(2-Bromo-thiazol-5-yl)-propan-1-ol

Sources & evidence

ORD record
ord-62fbda9905b4471ba02043843cca7ff8
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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