Water → 4-(Methylamino)-2-[(4-morpholinophenyl)amino]-5-nitropyrimidine

HRID 954918Notes

Reaction equation

HRID 954918 reaction equation
[CH2:26]1[O:27][CH2:28][CH2:29][CH2:30]1.[CH3:31][CH:32]([OH:33])[CH3:34].[Cl:1][c:2]1[n:3][cH:4][c:5]([N+:10](=[O:11])[O-:12])[c:6]([NH:8][CH3:9])[n:7]1.[NH2:13][c:14]1[cH:15][cH:16][c:17]([N:20]2[CH2:21][CH2:22][O:23][CH2:24][CH2:25]2)[cH:18][cH:19]1.[OH2:35]>>[c:2]1([NH:13][c:14]2[cH:15][cH:16][c:17]([N:20]3[CH2:21][CH2:22][O:23][CH2:24][CH2:25]3)[cH:18][cH:19]2)[n:3][cH:4][c:5]([N+:10](=[O:11])[O-:12])[c:6]([NH:8][CH3:9])[n:7]1

Participants

6

Reactant 5

HCID 962WaterHCID 3776IsopropanolHCID 8028TetrahydrofuranHCID 75655Benzenamine, 4-(4-morpholinyl)-HCID 71472322-chloro-N-methyl-5-nitropyrimidin-4-amine

Product 1

HCID 210775724-(Methylamino)-2-[(4-morpholinophenyl)amino]-5-nitropyrimidine

Sources & evidence

ORD record
ord-e310c883c09046038185e21d46c8ea25
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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