Dimethylformamide → N-(5-(4-acetylpiperazin-1-yl)pyridin-2-yl)-2-(6-chloro-5-methylpyridin-3-yl)acetamide
Reaction equation
[CH3:67][CH2:68][O:69][C:70](=[O:71])[CH3:72].[CH:53]([N:54]([CH2:55][CH3:56])[CH:57]([CH3:58])[CH3:59])([CH3:60])[CH3:61].[Cl:1][c:2]1[c:3]([CH3:12])[cH:4][c:5]([CH2:8][C:9](=[O:10])[OH:11])[cH:6][n:7]1.[NH2:13][c:14]1[cH:15][cH:16][c:17]([N:20]2[CH2:21][CH2:22][N:23]([C:26]([CH3:27])=[O:28])[CH2:24][CH2:25]2)[cH:18][n:19]1.[O:62]=[CH:63][N:64]([CH3:65])[CH3:66].[P-:29]([F:30])([F:31])([F:32])([F:33])([F:34])[F:35].[n:36]1([O:37][C:38]([N:39]([CH3:40])[CH3:41])=[N+:42]([CH3:43])[CH3:44])[c:45]2[n:46][cH:47][cH:48][cH:49][c:50]2[n:51][n:52]1>>[Cl:1][c:2]1[c:3]([CH3:12])[cH:4][c:5]([CH2:8][C:9](=[O:11])[NH:13][c:14]2[cH:15][cH:16][c:17]([N:20]3[CH2:21][CH2:22][N:23]([C:26]([CH3:27])=[O:28])[CH2:24][CH2:25]3)[cH:18][n:19]2)[cH:6][n:7]1Participants
8
Reactant 7
HCID 6228Dimethylformamide
HCID 8857Ethyl Acetate
HCID 9886Hexafluorophosphate
HCID 81531Diisopropylethylamine
HCID 4641409(Dimethylamino)-N,N-dimethyl(3H-(1,2,3)triazolo(4,5-b)pyridin-3-yloxy)methaniminium
HCID 284116891-(4-(6-Aminopyridin-3-YL)piperazin-1-YL)ethan-1-one
HCID 552673572-(6-Chloro-5-methylpyridin-3-yl)acetic acidProduct 1
Sources & evidence
- ORD record
- ord-1251007f67f54ee39ca81e922f1e7acd
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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