Tetrahydrofuran → 6-Methyl-3-pyridinecarboxaldehyde

HRID 955232Notes

Reaction equation

HRID 955232 reaction equation
[Al+3:13].[CH2:24]1[O:25][CH2:26][CH2:27][CH2:28]1.[CH3:18][CH2:19][O:20][C:21](=[O:22])[CH3:23].[CH3:1][c:2]1[n:3][cH:4][c:5]([C:6](=[O:7])[O:8][CH3:9])[cH:10][cH:11]1.[H-:12].[H-:15].[H-:16].[H-:17].[Li+:14]>>[CH3:1][c:2]1[n:3][cH:4][c:5]([CH:6]=[O:7])[cH:10][cH:11]1

Participants

7

Reactant 6

HCID 8028TetrahydrofuranHCID 8857Ethyl AcetateHCID 28486Lithium ionHCID 104727Aluminum CationHCID 166653Hydride4×HCID 231548Methyl 6-methylnicotinate

Product 1

HCID 101925666-Methyl-3-pyridinecarboxaldehyde

Sources & evidence

ORD record
ord-3098c28c10564cda9d8c4c59755ff9c8
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

Loading…