Potassium Cation → 1-(4-Bromophenyl)-3,5-dimethylpiperazine

HRID 955762Notes

Reaction equation

HRID 955762 reaction equation
[Br:1][c:2]1[cH:3][cH:4][c:5]([I:8])[cH:6][cH:7]1.[CH3:39][CH:40]1[NH:41][CH:42]([CH3:46])[CH2:43][NH:44][CH2:45]1.[CH3:47][CH2:48][O:49][C:50]([CH3:51])=[O:52].[Cu:53][I:54].[K+:36].[K+:37].[K+:38].[O:55]=[CH:56][N:57]([CH3:58])[CH3:59].[OH:9][c:10]1[c:11](-[c:12]2[c:13]3[c:14]([cH:15][cH:16][cH:17][cH:18]3)[cH:19][cH:20][c:21]2[OH:22])[c:23]2[c:24]([cH:25][cH:26][cH:27][cH:28]2)[cH:29][cH:30]1.[P:31]([O-:32])([O-:33])([O-:34])=[O:35]>>[Br:1][c:2]1[cH:3][cH:4][c:5]([N:44]2[CH2:43][CH:42]([CH3:46])[NH:41][CH:40]([CH3:39])[CH2:45]2)[cH:6][cH:7]1

Participants

9

Reactant 8

HCID 813Potassium Cation3×HCID 1061PhosphateHCID 6228DimethylformamideHCID 8857Ethyl AcetateHCID 115221-Bromo-4-iodobenzeneHCID 11762BinolHCID 24350Copper(1+) iodide; Copper(I) iodide; Cuprous iodide; Cuprous iodide (CuI)HCID 660562,6-Dimethylpiperazine

Product 1

HCID 674484391-(4-Bromophenyl)-3,5-dimethylpiperazine

Sources & evidence

ORD record
ord-361d107b6af04572a9759bcd02454914
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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