HRID95651

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID6228

Dimethylformamide

C3H7NO

HCID6344

Dichloromethane

CH2Cl2

HCID8471

Triethylamine

C6H15N

HCID65578

Ethanedioyl dichloride

C2Cl2O2

HCID17858792

未命名化合物

HCID17858807

未命名化合物

PRODUCTS

产物

HCID58778583

Ethyl (5-chloro-2-fluoro-4-((6-fluoro-1-methyl-3-indolylcarbonyl)amino)phenyl)acetate

C20H17ClF2N2O3

来源与证据

来源类型: Open Reaction Database
ORD记录: ord-004d9532bc8d409eac9aaec4c1f10b62
来源数据集: Training data from https://doi.org/10.1039/C8SC04228D (2/10)
DOI: 10.1039/C8SC04228D
来源说明: Training data from https://doi.org/10.1039/C8SC04228D (2/10)

反应SMILES

[CH2:48]([Cl:49])[Cl:50].[CH3:41][CH2:42][N:43]([CH2:44][CH3:45])[CH2:46][CH3:47].[Cl:20][C:21]([C:22]([Cl:23])=[O:24])=[O:25].[F:1][c:2]1[cH:3][cH:4][c:5]2[c:6]([C:12](=[O:13])[OH:14])[cH:7][n:8]([CH3:11])[c:9]2[cH:10]1.[NH2:26][c:27]1[cH:28][c:29]([F:40])[c:30]([CH2:34][C:35](=[O:36])[O:37][CH2:38][CH3:39])[cH:31][c:32]1[Cl:33].[O:15]=[CH:16][N:17]([CH3:18])[CH3:19]>>[F:1][c:2]1[cH:3][cH:4][c:5]2[c:6]([C:12](=[O:14])[NH:26][c:27]3[cH:28][c:29]([F:40])[c:30]([CH2:34][C:35](=[O:36])[O:37][CH2:38][CH3:39])[cH:31][c:32]3[Cl:33])[cH:7][n:8]([CH3:11])[c:9]2[cH:10]1