Dichloromethane → Tert-butyl 4-{[7-({[3-cyano-5-(trifluoromethyl)phenyl]-amino}carbonyl)-5,6,7,8-tetrahydronaphthalen-2-yl]oxy}pyridine-2-carboxylate
Reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[c:8]1[n:9][cH:10][cH:11][c:12]([O:14][c:15]2[cH:16][cH:17][c:18]3[c:23]([cH:24]2)[CH2:22][CH:21]([C:25](=[O:26])[OH:27])[CH2:20][CH2:19]3)[cH:13]1.[CH3:41][CH2:42][N:43]=[C:44]=[N:45][CH2:46][CH2:47][CH2:48][N:49]([CH3:50])[CH3:51].[CH3:52][N:53]([c:54]1[cH:55][cH:56][n:57][cH:58][cH:59]1)[CH3:60].[CH3:64][CH2:65][O:66][C:67]([CH3:68])=[O:69].[Cl:61][CH2:62][Cl:63].[NH2:28][c:29]1[cH:30][c:31]([C:32]#[N:33])[cH:34][c:35]([C:37]([F:38])([F:39])[F:40])[cH:36]1>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[c:8]1[n:9][cH:10][cH:11][c:12]([O:14][c:15]2[cH:16][cH:17][c:18]3[c:23]([cH:24]2)[CH2:22][CH:21]([C:25](=[O:26])[NH:28][c:29]2[cH:30][c:31]([C:32]#[N:33])[cH:34][c:35]([C:37]([F:38])([F:39])[F:40])[cH:36]2)[CH2:20][CH2:19]3)[cH:13]1Participants
7
Reactant 6
Product 1
Sources & evidence
- ORD record
- ord-b93ddab96c6a4532abcf7aefd8a8e4c6
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (2/10)
Reaction notes
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