1,2-Dichloroethane → 4-Chloro-7-methoxyquinazolin-6-yl acetate

HRID 957168Notes

Reaction equation

HRID 957168 reaction equation
[Cl:29][CH2:30][CH2:31][Cl:32].[Cl:6][C:7]([C:8]([Cl:9])=[O:10])=[O:11].[O:1]=[CH:2][N:3]([CH3:4])[CH3:5].[OH:12][c:13]1[n:14][cH:15][n:16][c:17]2[cH:18][c:19]([O:27][CH3:28])[c:20]([O:23][C:24]([CH3:25])=[O:26])[cH:21][c:22]12>>[Cl:6][c:13]1[n:14][cH:15][n:16][c:17]2[cH:18][c:19]([O:27][CH3:28])[c:20]([O:23][C:24]([CH3:25])=[O:26])[cH:21][c:22]12

Participants

5

Reactant 4

HCID 111,2-DichloroethaneHCID 6228DimethylformamideHCID 65578Oxalyl chlorideHCID 178486873HCID 178486873, compound

Product 1

HCID 220221604-Chloro-7-methoxyquinazolin-6-yl acetate

Sources & evidence

ORD record
ord-d99778fa876e4678bae67424a7911336
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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