Benzene → 2-(1-Benzyl-4-heptyl-4-piperidyloxy)-ethanol
Reaction equation
[CH2:10]([I:11])[CH3:12].[CH2:14]([c:15]1[cH:16][cH:17][cH:18][cH:19][cH:20]1)[N:21]1[CH2:22][CH2:23][C:24]2([O:25][CH2:26][CH2:27][O:28]2)[CH2:29][CH2:30]1.[CH2:1]([CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH3:7])[Br:8].[I:13].[Mg:9].[cH:31]1[cH:32][cH:33][cH:34][cH:35][cH:36]1>>[CH2:1]([CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH3:7])[C:24]1([O:28][CH2:27][CH2:26][OH:25])[CH2:23][CH2:22][N:21]([CH2:14][c:15]2[cH:16][cH:17][cH:18][cH:19][cH:20]2)[CH2:30][CH2:29]1Participants
7
Sources & evidence
- ORD record
- ord-f57d695ca9b341b2bdd8e87a556d7255
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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