Water → tert-butyl 4-(1-(4-methoxybenzyl)-3-((1-(4-methoxybenzyl)-1H-pyrazol-4-yl)ethynyl)-5-phenyl-1H-pyrazolo[3,4-b]pyridin-4-yl)piperazine-1-carboxylate

HRID 958270Notes

Reaction equation

[C:1](#[CH:2])[c:3]1[cH:4][n:5][n:6]([CH2:8][c:9]2[cH:10][cH:11][c:12]([O:15][CH3:16])[cH:13][cH:14]2)[cH:7]1.[CH2:62]1[O:63][CH2:64][CH2:65][CH2:66]1.[CH3:56][CH2:57][O:58][C:59](=[O:60])[CH3:61].[I:17][c:18]1[n:19][n:20]([CH2:46][c:47]2[cH:48][cH:49][c:50]([O:53][CH3:54])[cH:51][cH:52]2)[c:21]2[n:22][cH:23][c:24](-[c:40]3[cH:41][cH:42][cH:43][cH:44][cH:45]3)[c:25]([N:27]3[CH2:28][CH2:29][N:30]([C:33](=[O:34])[O:35][C:36]([CH3:37])([CH3:38])[CH3:39])[CH2:31][CH2:32]3)[c:26]12.[OH2:55].[Pd:67]([Cl:68])[Cl:69].[c:70]1([P:71]([c:72]2[cH:73][cH:74][cH:75][cH:76][cH:77]2)[c:78]2[cH:79][cH:80][cH:81][cH:82][cH:83]2)[cH:84][cH:85][cH:86][cH:87][cH:88]1.[c:89]1([P:90]([c:91]2[cH:92][cH:93][cH:94][cH:95][cH:96]2)[c:97]2[cH:98][cH:99][cH:100][cH:101][cH:102]2)[cH:103][cH:104][cH:105][cH:106][cH:107]1>>[C:1](#[C:2][c:18]1[n:19][n:20]([CH2:46][c:47]2[cH:48][cH:49][c:50]([O:53][CH3:54])[cH:51][cH:52]2)[c:21]2[n:22][cH:23][c:24](-[c:40]3[cH:41][cH:42][cH:43][cH:44][cH:45]3)[c:25]([N:27]3[CH2:28][CH2:29][N:30]([C:33](=[O:34])[O:35][C:36]([CH3:37])([CH3:38])[CH3:39])[CH2:31][CH2:32]3)[c:26]12)[c:3]1[cH:4][n:5][n:6]([CH2:8][c:9]2[cH:10][cH:11][c:12]([O:15][CH3:16])[cH:13][cH:14]2)[cH:7]1