Dichloromethane → 1-Benzyl 2-methyl 4-(((4-methylphenyl)sulfonyl)oxy)-1,2-pyrrolidinedicarboxylate

HRID 958440Notes

Reaction equation

HRID 958440 reaction equation
[CH2:48]([Cl:49])[Cl:50].[CH3:19][O:20][C:21]([CH:22]1[N:23]([C:28](=[O:29])[O:30][CH2:31][c:32]2[cH:33][cH:34][cH:35][cH:36][cH:37]2)[CH2:24][CH:25]([OH:27])[CH2:26]1)=[O:38].[CH3:1][CH2:2][N:3]([CH2:4][CH3:5])[CH2:6][CH3:7].[CH3:39][N:40]([CH3:41])[c:42]1[cH:43][cH:44][n:45][cH:46][cH:47]1.[c:8]1([CH3:18])[cH:9][cH:10][c:11]([S:14](=[O:15])(=[O:16])[Cl:17])[cH:12][cH:13]1>>[c:8]1([CH3:18])[cH:9][cH:10][c:11]([S:14](=[O:15])(=[O:16])[O:27][CH:25]2[CH2:24][N:23]([C:28](=[O:29])[O:30][CH2:31][c:32]3[cH:33][cH:34][cH:35][cH:36][cH:37]3)[CH:22]([C:21]([O:20][CH3:19])=[O:38])[CH2:26]2)[cH:12][cH:13]1

Participants

6

Reactant 5

HCID 6344DichloromethaneHCID 73974-Toluenesulfonyl chlorideHCID 8471TriethylamineHCID 142844-(Dimethylamino)pyridineHCID 3253131-Benzyl 2-methyl 4-hydroxypyrrolidine-1,2-dicarboxylate

Product 1

HCID 2865661-Benzyl 2-methyl 4-(((4-methylphenyl)sulfonyl)oxy)-1,2-pyrrolidinedicarboxylate

Sources & evidence

ORD record
ord-7ce2ad53977b403abab73569b9d057be
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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