Hydrochloric Acid → N-{1-[3-(3-ethoxy-4-methoxybenzyl)-5-oxo-4,5-dihydro-1,2,4-triazin-6-yl]propyl}2-(1-hydroxyethyl)-5-phenylpentanamide

HRID 958928Notes

Reaction equation

HRID 958928 reaction equation
[CH2:27]([N:28]([CH:29]([CH3:30])[CH3:31])[CH:32]([CH3:33])[CH3:34])[CH3:35].[CH3:37][N:38]([CH3:39])[CH2:40][CH2:41][CH2:42][N:43]=[C:44]=[N:45][CH2:46][CH3:47].[ClH:36].[NH2:48][CH:49]([CH2:50][CH3:51])[c:52]1[c:53](=[O:70])[nH:54][c:55]([CH2:58][c:59]2[cH:60][c:61]([O:67][CH2:68][CH3:69])[c:62]([O:65][CH3:66])[cH:63][cH:64]2)[n:56][n:57]1.[OH:17][n:18]1[c:19]2[cH:20][cH:21][cH:22][cH:23][c:24]2[n:25][n:26]1.[OH:1][CH:2]([CH3:3])[CH:4]([C:5](=[O:6])[OH:7])[CH2:8][CH2:9][CH2:10][c:11]1[cH:12][cH:13][cH:14][cH:15][cH:16]1>>[OH:1][CH:2]([CH3:3])[CH:4]([C:5](=[O:7])[NH:48][CH:49]([CH2:50][CH3:51])[c:52]1[c:53](=[O:70])[nH:54][c:55]([CH2:58][c:59]2[cH:60][c:61]([O:67][CH2:68][CH3:69])[c:62]([O:65][CH3:66])[cH:63][cH:64]2)[n:56][n:57]1)[CH2:8][CH2:9][CH2:10][c:11]1[cH:12][cH:13][cH:14][cH:15][cH:16]1

Participants

7

Reactant 6

HCID 313Hydrochloric AcidHCID 159081-Ethyl-3-(3'-dimethylaminopropyl)carbodiimideHCID 757711-HydroxybenzotriazoleHCID 81531DiisopropylethylamineHCID 183340382-(1-Hydroxyethyl)-5-phenylpentanoic acidHCID 1358247386-(1-aminopropyl)-3-(3-ethoxy-4-methoxybenzyl)-1,2,4-triazin-5(4H)-one

Product 1

HCID 135824728N-{1-[3-(3-ethoxy-4-methoxybenzyl)-5-oxo-4,5-dihydro-1,2,4-triazin-6-yl]propyl}2-(1-hydroxyethyl)-5-phenylpentanamide

Sources & evidence

ORD record
ord-35bc9f0a14ef4b16952973e54ca1d60c
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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