Ammonium → 1-[5-Chloro-2-(trifluoromethoxy)phenyl]methanamine

HRID 959034Notes

Reaction equation

HRID 959034 reaction equation
[CH2:40]1[O:41][CH2:42][CH2:43][CH2:44]1.[CH3:49][CH2:50][O:51][CH2:52][CH3:53].[CH3:54][OH:55].[Cl:37][CH2:38][Cl:39].[ClH:36].[N:20](=[N+:21]=[N-:22])[CH2:23][c:24]1[c:25]([O:31][C:32]([F:33])([F:34])[F:35])[cH:26][cH:27][c:28]([Cl:30])[cH:29]1.[NH4+:45].[Na+:48].[OH-:46].[OH-:47].[c:1]1([P:2]([c:3]2[cH:4][cH:5][cH:6][cH:7][cH:8]2)[c:9]2[cH:10][cH:11][cH:12][cH:13][cH:14]2)[cH:15][cH:16][cH:17][cH:18][cH:19]1>>[NH2:20][CH2:23][c:24]1[c:25]([O:31][C:32]([F:33])([F:34])[F:35])[cH:26][cH:27][c:28]([Cl:30])[cH:29]1

Participants

11

Reactant 10

HCID 223AmmoniumHCID 313Hydrochloric AcidHCID 887MethanolHCID 923Sodium ionHCID 961Hydroxide2×HCID 3283Diethyl EtherHCID 6344DichloromethaneHCID 8028TetrahydrofuranHCID 11776TriphenylphosphineHCID 57885582Benzene, 2-(azidomethyl)-4-chloro-1-(trifluoromethoxy)-

Product 1

HCID 468355271-[5-Chloro-2-(trifluoromethoxy)phenyl]methanamine

Sources & evidence

ORD record
ord-47c4ab085a83416781d071f6ac6aa07e
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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