Dichloromethane → Benzyl 4-Hydroxy-1-piperidinecarboxylate

HRID 959221Notes

Reaction equation

HRID 959221 reaction equation
[CH2:26]([Cl:27])[Cl:28].[CH3:19][CH2:20][N:21]([CH2:22][CH3:23])[CH2:24][CH3:25].[Cl:1][C:2](=[O:3])[O:4][CH2:5][c:6]1[cH:7][cH:8][cH:9][cH:10][cH:11]1.[OH:12][CH:13]1[CH2:14][CH2:15][NH:16][CH2:17][CH2:18]1>>[C:2](=[O:3])([O:4][CH2:5][c:6]1[cH:7][cH:8][cH:9][cH:10][cH:11]1)[N:16]1[CH2:15][CH2:14][CH:13]([OH:12])[CH2:18][CH2:17]1

Participants

5

Reactant 4

HCID 6344DichloromethaneHCID 8471TriethylamineHCID 10387Benzyl chloroformateHCID 79341Piperidin-4-ol

Product 1

HCID 2794620Benzyl 4-Hydroxy-1-piperidinecarboxylate

Sources & evidence

ORD record
ord-095e23fff832416ebef8c2b33cbbc02a
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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