Water → N-(5-chloropyridin-2-yl)-5-methyl-2-nitrobenzamide

HRID 960576Notes

Reaction equation

HRID 960576 reaction equation
[CH3:14][N:15]([CH3:16])[CH:17]=[O:18].[CH3:1][c:2]1[cH:3][cH:4][c:5]([N+:11](=[O:12])[O-:13])[c:6]([C:7](=[O:8])[OH:9])[cH:10]1.[Cl:19][C:20]([C:21]([Cl:22])=[O:23])=[O:24].[Cl:33][CH2:34][Cl:35].[NH2:25][c:26]1[n:27][cH:28][c:29]([Cl:32])[cH:30][cH:31]1.[OH2:36].[cH:37]1[cH:38][cH:39][n:40][cH:41][cH:42]1>>[CH3:1][c:2]1[cH:3][cH:4][c:5]([N+:11](=[O:12])[O-:13])[c:6]([C:7](=[O:9])[NH:25][c:26]2[n:27][cH:28][c:29]([Cl:32])[cH:30][cH:31]2)[cH:10]1

Participants

8

Reactant 7

HCID 962WaterHCID 1049PyridineHCID 6228DimethylformamideHCID 6344DichloromethaneHCID 183715-Methyl-2-nitrobenzoic acidHCID 65578Oxalyl chlorideHCID 661742-Amino-5-chloropyridine

Product 1

HCID 3562519N-(5-chloropyridin-2-yl)-5-methyl-2-nitrobenzamide

Sources & evidence

ORD record
ord-2faeb7f1d6b6413b9fde271b3e3d95af
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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