Acetonitrile → 4-(4-Butylphenylethynyl)phenylamine

HRID 961256Notes

Reaction equation

HRID 961256 reaction equation
[C:9](#[CH:10])[c:11]1[cH:12][cH:13][c:14]([CH2:17][CH2:18][CH2:19][CH3:20])[cH:15][cH:16]1.[CH3:21][C:22]#[N:23].[Cu:24][I:25].[I:1][c:2]1[cH:3][cH:4][c:5]([NH2:6])[cH:7][cH:8]1.[Pd:26]([Cl:27])[Cl:28].[c:29]1([P:30]([c:31]2[cH:32][cH:33][cH:34][cH:35][cH:36]2)[c:37]2[cH:38][cH:39][cH:40][cH:41][cH:42]2)[cH:43][cH:44][cH:45][cH:46][cH:47]1.[c:48]1([P:49]([c:50]2[cH:51][cH:52][cH:53][cH:54][cH:55]2)[c:56]2[cH:57][cH:58][cH:59][cH:60][cH:61]2)[cH:62][cH:63][cH:64][cH:65][cH:66]1>>[c:2]1([C:10]#[C:9][c:11]2[cH:12][cH:13][c:14]([CH2:17][CH2:18][CH2:19][CH3:20])[cH:15][cH:16]2)[cH:3][cH:4][c:5]([NH2:6])[cH:7][cH:8]1

Participants

7

Reactant 6

HCID 6342AcetonitrileHCID 108934-IodoanilineHCID 11776Triphenylphosphine2×HCID 24290Palladium ChlorideHCID 24350Copper(1+) iodide; Copper(I) iodide; Cuprous iodide; Cuprous iodide (CuI)HCID 27751321-Butyl-4-ethynylbenzene

Product 1

HCID 575545094-(4-Butylphenylethynyl)phenylamine

Sources & evidence

ORD record
ord-eddd7e432b084cb6b8dd794939927042
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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