Sodium ion → 2-Amino-1-(1-benzofuran-2-yl)ethan-1-ol

HRID 961518Notes

Reaction equation

HRID 961518 reaction equation
[Al+3:19].[CH3:1][Si:2]([CH3:3])([CH3:4])[C:5]#[N:6].[CH:7](=[O:8])[c:9]1[o:10][c:11]2[c:12]([cH:13]1)[cH:14][cH:15][cH:16][cH:17]2.[H-:18].[H-:21].[H-:22].[H-:23].[I-:26].[I-:28].[Li+:20].[Na+:25].[OH-:24].[OH2:29].[Zn+2:27]>>[CH2:5]([NH2:6])[CH:7]([OH:8])[c:9]1[o:10][c:11]2[c:12]([cH:13]1)[cH:14][cH:15][cH:16][cH:17]2

Participants

11

Reactant 10

HCID 923Sodium ionHCID 961HydroxideHCID 962WaterHCID 28486Lithium ionHCID 30165Iodide Ion2×HCID 32051Zinc(2+)HCID 613412-BenzofurancarboxaldehydeHCID 82115Trimethylsilyl cyanideHCID 104727Aluminum CationHCID 166653Hydride4×

Product 1

HCID 128143572-Amino-1-(1-benzofuran-2-yl)ethan-1-ol

Sources & evidence

ORD record
ord-deb0f79d345b4b2fa66081c44316ac22
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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