Tetrahydrofuran → 3-Bromo-5-(trifluoromethyl)benzyl bromide

HRID 961600Notes

Reaction equation

HRID 961600 reaction equation
[Br:1][c:2]1[cH:3][c:4]([CH2:12][OH:13])[cH:5][c:6]([C:8]([F:9])([F:10])[F:11])[cH:7]1.[Br:33][N:34]1[C:35](=[O:36])[CH2:37][CH2:38][C:39]1=[O:40].[CH3:46][CH2:47][O:48][C:49](=[O:50])[CH3:51].[O:41]1[CH2:42][CH2:43][CH2:44][CH2:45]1.[c:14]1([P:15]([c:16]2[cH:17][cH:18][cH:19][cH:20][cH:21]2)[c:22]2[cH:23][cH:24][cH:25][cH:26][cH:27]2)[cH:28][cH:29][cH:30][cH:31][cH:32]1>>[Br:1][c:2]1[cH:3][c:4]([CH2:12][Br:33])[cH:5][c:6]([C:8]([F:9])([F:10])[F:11])[cH:7]1

Participants

6

Reactant 5

HCID 8028TetrahydrofuranHCID 8857Ethyl AcetateHCID 11776TriphenylphosphineHCID 67184N-bromobutanimideHCID 29919767[3-Bromo-5-(trifluoromethyl)phenyl]methanol

Product 1

HCID 223242723-Bromo-5-(trifluoromethyl)benzyl bromide

Sources & evidence

ORD record
ord-d580b28e00df45e8865b13bb7e21e245
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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