Hydrochloric Acid → 2-Bromo-5-(4-fluorobenzyl)thiophene
Reaction equation
[Br:9][c:10]1[s:11][cH:12][cH:13][cH:14]1.[CH2:25]1[O:26][CH2:27][CH2:28][CH2:29]1.[CH3:2][CH:3]([N-:4][CH:5]([CH3:6])[CH3:7])[CH3:8].[ClH:24].[F:15][c:16]1[cH:17][cH:18][c:19]([CH2:20][Br:21])[cH:22][cH:23]1.[Li+:1]>>[Br:9][c:10]1[s:11][c:12]([CH2:20][c:19]2[cH:18][cH:17][c:16]([F:15])[cH:23][cH:22]2)[cH:13][cH:14]1Participants
7
Sources & evidence
- ORD record
- ord-5a186cfe13b6442d8e71a43f3ebd8319
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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