Triethylamine → HCID 70585819, compound

HRID 972109Notes

Reaction equation

HRID 972109 reaction equation
N[N:2]1[C:6](=[O:7])[C:5]([CH3:8])=[C:4]([CH3:9])[C:3]1=[O:10].C([N:13]([CH2:16][CH3:17])CC)C.[C:18](Cl)(=[O:22])[C:19](C)=C>ClCCl>[NH2:13][C:16](=[CH2:17])[C:18](=[O:22])[CH2:19][N:2]1[C:6](=[O:7])[C:5]([CH3:8])=[C:4]([CH3:9])[C:3]1=[O:10]

Participants

5

Reactant 3

HCID 8471TriethylamineHCID 13528Methacryloyl chlorideHCID 203467851-Amino-3,4-dimethyl-1H-pyrrole-2,5-dione

Product 1

HCID 70585819HCID 70585819, compound

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent

Conditions

Temperature
0 °C

Procedure

140.0 g (1.0 mol) of N-amino-dimethylmaleimide and 111.3 g (1.1 mols) of triethylamine (dried over NaOH) are dissolved in 2,500 ml of dichloromethane and the solution is cooled to 0° C. 104.5 g (1.0 mol) of methacrylic acid chloride are allowed to run dropwise into this solution at such a rate that the temperature does not 10° C. When the reaction has ended, the mixture is heated to 40° C. and then stirred for one hour at this temperature.

Workup

  1. customdoes not 10° C
  2. temperaturethe mixture is heated to 40° C.

Sources & evidence

ORD record
ord-f7fd866117f34c35be8ccc915b749785
Source dataset
uspto-grants-1979_07
Patent number
US04163097

Reaction notes

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