Sodium Bicarbonate → HCID 21988158, compound

HRID 9722Notes

Reaction equation

HRID 9722 reaction equation
[N+:1]([C:4]1[CH:15]=[CH:14][C:7]2[N:8]([CH3:13])[C:9](=O)[CH2:10][S:11][C:6]=2[CH:5]=1)([O-:3])=[O:2].C(=O)(O)[O-].[Na+]>C1COCC1>[N+:1]([C:4]1[CH:15]=[CH:14][C:7]2[N:8]([CH3:13])[CH:9]=[CH:10][S:11][C:6]=2[CH:5]=1)([O-:3])=[O:2]

Participants

4

Reactant 2

HCID 516892Sodium BicarbonateHCID 218777807-Nitro-4-methyl-4H-benzo[1,4]thiazin-3-one

Product 1

HCID 21988158HCID 21988158, compound

Reagents, catalysts & solvents 1

HCID 8028TetrahydrofuranSolvent2×

Procedure

7 g 7-Nitro-4-methyl-4H-benzo[1,4]thiazin-3-one (from j)) in 10 ml THF were treated dropwise with 67.57 ml 2M borane dimethyl sulfide complex in THF at room temperature. After 16 hrs the mixture was poured into saturated aqueous sodium bicarbonate and extracted with ethyl acetate. The solvent was evaporated and the solid residue triturated with ether.

Workup

  1. extractionextracted with ethyl acetate
  2. customThe solvent was evaporated
  3. customthe solid residue triturated with ether

Sources & evidence

ORD record
ord-6bad55cfa06a4e3ca987226d8d6dc084
Source dataset
uspto-grants-2006_08
Patent number
US07091345B2

Reaction notes

Loading…