Hydrochloric Acid → 1-[1-[3-[4-amino-3-chloro-5-(trifluoromethyl)phenyl]-2-[4-(2-oxo-4,5-dihydro-1H-1,3-benzodiazepin-3-yl)piperidine-1-carbonyl]oxypropanoyl]piperidin-4-yl]piperidine-4-carboxylic acid
Reaction equation
[CH2:59]1[O:60][CH2:61][CH2:62][CH2:63]1.[ClH:57].[Li+:2].[NH2:3][c:4]1[c:5]([Cl:56])[cH:6][c:7]([CH2:14][CH:15]([C:16](=[O:17])[N:18]2[CH2:19][CH2:20][CH:21]([N:24]3[CH2:25][CH2:26][CH:27]([C:30](=[O:31])[O:32][CH2:33][CH3:34])[CH2:28][CH2:29]3)[CH2:22][CH2:23]2)[O:35][C:36](=[O:37])[N:38]2[CH2:39][CH2:40][CH:41]([N:44]3[C:45](=[O:55])[NH:46][c:47]4[c:48]([cH:51][cH:52][cH:53][cH:54]4)[CH2:49][CH2:50]3)[CH2:42][CH2:43]2)[cH:8][c:9]1[C:10]([F:11])([F:12])[F:13].[OH-:1].[OH2:58]>>[NH2:3][c:4]1[c:5]([Cl:56])[cH:6][c:7]([CH2:14][CH:15]([C:16](=[O:17])[N:18]2[CH2:19][CH2:20][CH:21]([N:24]3[CH2:25][CH2:26][CH:27]([C:30](=[O:31])[OH:32])[CH2:28][CH2:29]3)[CH2:22][CH2:23]2)[O:35][C:36](=[O:37])[N:38]2[CH2:39][CH2:40][CH:41]([N:44]3[C:45](=[O:55])[NH:46][c:47]4[c:48]([cH:51][cH:52][cH:53][cH:54]4)[CH2:49][CH2:50]3)[CH2:42][CH2:43]2)[cH:8][c:9]1[C:10]([F:11])([F:12])[F:13]Participants
7
Reactant 6
Product 1
Sources & evidence
- ORD record
- ord-515f87cec170453785ddc2348cdbff51
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (2/10)
Reaction notes
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