Hydrochloric Acid → HCID 19972094, compound

HRID 975604Notes

Reaction equation

HRID 975604 reaction equation
[C:1]([NH:9][CH2:10][C:11](=[N:19][NH:20][C:21]([NH:23][C:24]1[CH:29]=[CH:28][C:27]([O:30][C:31]([F:34])([F:33])[F:32])=[CH:26][CH:25]=1)=[O:22])[C:12]1[CH:17]=[CH:16][CH:15]=[C:14](Cl)[CH:13]=1)(=[O:8])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.C([BH3-])#N.[Na+].[ClH:39]>CO>[C:1]([NH:9][CH2:10][CH:11]([NH:19][NH:20][C:21]([NH:23][C:24]1[CH:25]=[CH:26][C:27]([O:30][C:31]([F:33])([F:34])[F:32])=[CH:28][CH:29]=1)=[O:22])[C:12]1[CH:17]=[CH:16][C:15]([Cl:39])=[CH:14][CH:13]=1)(=[O:8])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1

Participants

5

Reactant 3

HCID 313Hydrochloric AcidHCID 5003444Sodium cyanoborohydrideHCID 53683221HCID 53683221, compound

Product 1

HCID 19972094HCID 19972094, compound

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

In 10 ml of methanol was suspended 0.30 g (0.59 mmole) of 2-[2-benzoylamino-l-(3-chlorophenyl)ethylidene]-N-(4-trifluoromethoxyphenyl)hydrazinecarboxamide, and 0.07 g (1 mmole) of sodium cyanoborohydride was added to the resulting suspension. The resulting mixture was adjusted to pH 4 to 6 with a methanolic solution of hydrogen chloride at room temperature and subjected to reaction.

Workup

  1. additionwas added to the resulting suspension
  2. customsubjected to reaction

Sources & evidence

ORD record
ord-8db07af2006a49a38c38dd285c95bae6
Source dataset
uspto-grants-1997_03
Patent number
US05608109

Reaction notes

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