Hydrochloric Acid → HCID 19972088, compound

HRID 975605Notes

Reaction equation

HRID 975605 reaction equation
[CH2:1]([S:4][CH2:5][C:6](=[N:13][NH:14][C:15]([NH:17][C:18]1[CH:23]=[CH:22][C:21]([O:24][C:25]([F:28])([F:27])[F:26])=[CH:20][CH:19]=1)=[O:16])[C:7]1[CH:12]=[CH:11][CH:10]=[CH:9][CH:8]=1)[C:2]#[CH:3].C([BH3-])#N.[Na+].Cl>CO>[CH2:1]([S:4][CH2:5][CH:6]([NH:13][NH:14][C:15]([NH:17][C:18]1[CH:19]=[CH:20][C:21]([O:24][C:25]([F:28])([F:26])[F:27])=[CH:22][CH:23]=1)=[O:16])[C:7]1[CH:8]=[CH:9][CH:10]=[CH:11][CH:12]=1)[C:2]#[CH:3]

Participants

5

Reactant 3

HCID 313Hydrochloric AcidHCID 5003444Sodium cyanoborohydrideHCID 54084392HCID 54084392, compound

Product 1

HCID 19972088HCID 19972088, compound

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

In 10 ml of methanol was suspended 0.50 g (1.2 mmoles) of 2-[2-(2-propynylthio)-1-phenylethylidene]-N-(4-trifluoromethoxyphenyl)hydrazinecarboxamide, and 0.37 g (4.7 mmoles) of sodium cyanoborohydride was added to the resulting suspension. The resulting mixture was adjusted to pH 4 to 6 with a methanolic solution of hydrogen chloride at room temperature and subjected to reaction.

Workup

  1. additionwas added to the resulting suspension
  2. customsubjected to reaction

Sources & evidence

ORD record
ord-3b619355597e43b38c839b30ea97163c
Source dataset
uspto-grants-1997_03
Patent number
US05608109

Reaction notes

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