Sodium Bicarbonate → HCID 131719944, compound

HRID 977511Notes

Reaction equation

HRID 977511 reaction equation
[C:1]1(C)C=CC(S(O)(=O)=O)=CC=1.[NH2:12][C@@H:13]1[C:35](=[O:36])[N:15]2[C:16]([C:23]([O:25][CH:26]([O:28][C:29]([O:31][CH:32]([CH3:34])[CH3:33])=[O:30])[CH3:27])=[O:24])=[C:17](COC)[CH2:18][S:19][C@H:14]12.[C:37]([O-:40])(O)=O.[Na+]>C(OCC)(=O)C>[NH2:12][C@@H:13]1[C:35](=[O:36])[N:15]2[C:16]([C:23]([O:25][CH:26]([O:28][C:29]([O:31][CH:32]([CH3:33])[CH3:34])=[O:30])[CH3:27])=[O:24])=[C:17]([O:40][CH3:37])[CH:18]([CH3:1])[S:19][C@H:14]12

Participants

4

Reactant 2

HCID 516892Sodium BicarbonateHCID 131719151HCID 131719151, compound

Product 1

HCID 131719944HCID 131719944, compound

Reagents, catalysts & solvents 1

HCID 8857Ethyl AcetateSolvent

Procedure

2.53 g (4.6 mmol) of diastereomer mixture from Example 1 were taken up in a mixture of ethyl acetate and 5% strength aq. NaHCO3 solution and stirred for 5 min. The phases were separated, and the organic phase was washed with satd. aq. NaCl solution, dried with MgSO4 and concentrated in vacuo.

Workup

  1. customThe phases were separated
  2. washthe organic phase was washed with satd
  3. dry with materialaq. NaCl solution, dried with MgSO4
  4. concentrationconcentrated in vacuo

Sources & evidence

ORD record
ord-44469b49fe5f49cc929f3b4bafaaa39f
Source dataset
uspto-grants-1997_03
Patent number
US05614623

Reaction notes

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