Propyl mercaptan → HCID 13784989, compound

HRID 980244Notes

Reaction equation

HRID 980244 reaction equation
[NH2:1][C:2]1[CH:7]=[C:6]([Cl:8])[C:5]([OH:9])=[C:4]([Cl:10])[CH:3]=1.C(=O)([O-])[O-].[K+].[K+].C(S)CC.[Br:21][C:22]([F:28])([F:27])[C:23]([F:26])([F:25])Br>CN(C)C=O>[Br:21][C:22]([F:28])([F:27])[C:23]([F:26])([F:25])[O:9][C:5]1[C:6]([Cl:8])=[CH:7][C:2]([NH2:1])=[CH:3][C:4]=1[Cl:10]

Participants

6

Reactant 4

HCID 7848Propyl mercaptanHCID 11430Potassium CarbonateHCID 313011,2-Dibromo-1,1,2,2-tetrafluoroethaneHCID 800374-Amino-2,6-dichlorophenol

Product 1

HCID 13784989HCID 13784989, compound

Reagents, catalysts & solvents 1

HCID 6228DimethylformamideSolvent

Procedure

In a manner similar to Step A of Example 1, the reaction of 12.5 g 0.07 mole) 4-amino-2,6-dichlorophenol, 7.3 g (0.053 mole) potassium carbonate, 1.0 g (0.013 mole) propanethiol, 36.5 g (0.14 mole) 1,2-dibromotetrafluoroethane and 125 ml of N,N-dimethylformamide produced 3.7 g of 4-(2-bromo-1,1,2,2-tetrafluoroethoxy)-3,5-dichloroaniline as an oil.

Sources & evidence

ORD record
ord-21f3c1a04133482889c3b90baf73b12e
Source dataset
uspto-grants-1987_01
Patent number
US04636523

Reaction notes

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