1-Naphthaldehyde → HCID 9818341, compound

HRID 989005Notes

Reaction equation

HRID 989005 reaction equation
[NH2:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][N:3]=1.[C:8]([N+:12]#[C-:13])([CH3:11])([CH3:10])[CH3:9].[C:14]1([CH:24]=O)[C:23]2[C:18](=[CH:19][CH:20]=[CH:21][CH:22]=2)[CH:17]=[CH:16][CH:15]=1>Cl(O)(=O)(=O)=O>[C:8]([NH:12][C:13]1[N:3]2[CH:4]=[CH:5][CH:6]=[CH:7][C:2]2=[N:1][C:24]=1[C:14]1[C:23]2[C:18](=[CH:19][CH:20]=[CH:21][CH:22]=2)[CH:17]=[CH:16][CH:15]=1)([CH3:11])([CH3:10])[CH3:9]

Participants

5

Reactant 3

HCID 61951-NaphthaldehydeHCID 104392-AminopyridineHCID 23577Tert-Butyl isocyanide

Product 1

HCID 9818341HCID 9818341, compound

Reagents, catalysts & solvents 1

HCID 24247Perchloric AcidSolvent

Procedure

Compound (31) was prepared in accordance with general instructions 1 from 1.0 ml 2-aminopyridine solution (0.1 M, MC), 0.575 ml tert-butyl isocyanide solution (0.2 M, MC), 0.500 ml naphthalene-1-carbaldehyde solution (0.3 M, MC), and 10 μl perchloric acid (w=20%). Calculated mass 315.4; found mass 316.3 (ESI-MS)

Sources & evidence

ORD record
ord-e8286fa03dc14a53a0cbe72b87e2192e
Source dataset
uspto-grants-2003_10
Patent number
US06638933B2

Reaction notes

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