Water → Methyl 3-[(dipropylamino)carbonyl]-5-ethynylbenzoate

HRID 99753Notes

Reaction equation

HRID 99753 reaction equation
[Br:1][c:2]1[cH:3][c:4]([C:5](=[O:6])[O:7][CH3:8])[cH:9][c:10]([C:12](=[O:13])[N:14]([CH2:15][CH2:16][CH3:17])[CH2:18][CH2:19][CH3:20])[cH:11]1.[CH3:21][Si:22]([CH3:23])([CH3:24])[C:25]#[CH:26].[CH3:27][CH2:28][N:29]([CH2:30][CH3:31])[CH2:32][CH3:33].[Cu:35][I:36].[OH2:34]>>[c:2]1([C:25]#[CH:26])[cH:3][c:4]([C:5](=[O:6])[O:7][CH3:8])[cH:9][c:10]([C:12](=[O:13])[N:14]([CH2:15][CH2:16][CH3:17])[CH2:18][CH2:19][CH3:20])[cH:11]1

Participants

6

Reactant 5

HCID 962WaterHCID 8471TriethylamineHCID 24350Copper(1+) iodide; Copper(I) iodide; Cuprous iodide; Cuprous iodide (CuI)HCID 66111TrimethylsilylacetyleneHCID 21939662Methyl 3-bromo-5-(dipropylcarbamoyl)benzoate

Product 1

HCID 21086178Methyl 3-[(dipropylamino)carbonyl]-5-ethynylbenzoate

Sources & evidence

ORD record
ord-58f7540072a24671b635d5f22ac7de97
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Reaction notes

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