1,2-Dichloroethane → 5-chloro-2-[[3-methoxy-4-(4-methylimidazol-1-yl)phenyl]methylidene]-N-(5-morpholin-4-yl-2,3-dihydro-1H-inden-1-yl)pentanamide

HRID 99938Notes

Reaction equation

HRID 99938 reaction equation
[CH2:62]([Cl:63])[CH2:64][Cl:65].[Cl:13][CH2:14][CH2:15][CH2:16][C:17]([C:18](=[O:19])[OH:20])=[CH:21][c:22]1[cH:23][c:24]([O:34][CH3:35])[c:25](-[n:28]2[cH:29][n:30][c:31]([CH3:33])[cH:32]2)[cH:26][cH:27]1.[F:6][C:7]([F:8])([F:9])[C:10]([OH:11])=[O:12].[O:1]=[CH:2][N:3]([CH3:4])[CH3:5].[O:36]1[CH2:37][CH2:38][N:39]([c:42]2[cH:43][c:44]3[c:48]([cH:49][cH:50]2)[CH:47]([NH2:51])[CH2:46][CH2:45]3)[CH2:40][CH2:41]1.[OH:52][n:53]1[c:54]2[c:55]([cH:56][cH:57][cH:58][cH:59]2)[n:60][n:61]1>>[Cl:13][CH2:14][CH2:15][CH2:16][C:17]([C:18](=[O:20])[NH:51][CH:47]1[CH2:46][CH2:45][c:44]2[cH:43][c:42]([N:39]3[CH2:38][CH2:37][O:36][CH2:41][CH2:40]3)[cH:50][cH:49][c:48]21)=[CH:21][c:22]1[cH:23][c:24]([O:34][CH3:35])[c:25](-[n:28]2[cH:29][n:30][c:31]([CH3:33])[cH:32]2)[cH:26][cH:27]1

Participants

7

Reactant 6

HCID 111,2-DichloroethaneHCID 6228DimethylformamideHCID 6422Trifluoroacetic acidHCID 757711-HydroxybenzotriazoleHCID 668396445-Chloro-2-[[3-methoxy-4-(4-methylimidazol-1-yl)phenyl]methylidene]pentanoic acidHCID 669617445-Morpholin-4-yl-indan-1-ylamine

Product 1

HCID 772117575-chloro-2-[[3-methoxy-4-(4-methylimidazol-1-yl)phenyl]methylidene]-N-(5-morpholin-4-yl-2,3-dihydro-1H-inden-1-yl)pentanamide

Sources & evidence

ORD record
ord-efce1f819aa34abda1dbfccf9a1bd884
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Reaction notes

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