Grundinformationen
- Standard-SMILES
FCC1CO1- InChIKey
OIFAHDAXIUURLN-UHFFFAOYSA-N- Summenformel
- C3H5FO
- Durchschnittliche Molmasse
- 76,07 g/mol
- Monoisotopische Masse
- 76,032443
Überblick
Epifluorohydrin is a clear colorless liquid. (NTP, 1992)
Namen und Bezeichner
- Bevorzugter Name
- 1,2-Epoxy-3-fluoropropane
- IUPAC
- 2-(fluoromethyl)oxirane
- Lokaler Name
- 1,2-Epoxy-3-fluorpropan
- Englischer Name
- Epifluorohydrin
- Summenformel
- C3H5FO
- Molmasse
- 76.07
Namen und Synonyme
Weitere Namen anzeigen
Datenbank-Bezeichner
- CAS
503-09-3- PubChem CID
- 10418
- DTXSID
DTXSID4025244- UNII
- 0ZZ4ROH5IL
- EC Number
- 207-960-1
- Nikkaji
- J1.567I
Eigenschaften
Berechnete Struktureigenschaften
- XLogP
- -0,2
- Polarare Oberfläche (TPSA)
- 12,5 Ų
- H-Brücken-Donoren
- 0
- H-Brücken-Akzeptoren
- 2
- Frei drehbare Bindungen
- 1
- Schwere Atome
- 5
- Formalladung
- 0
- Komplexität
- 37,9
Experimentelle und physikochemische Eigenschaften
Physikochemische Eigenschaften
- Siedepunkt
- 85 · 85-86 °C (lit.)
- Dichte
- 1.067 g/mL · 1.067 g/mL at 25 °C (lit.)
- Brechungsindex
- 20 · n20/D 1.368(lit.)
- Flammpunkt
- 40 °F · 40 °F
- storage temp.
- 0 · 0-6°C
- Aggregatzustand
- liquid
- Farbe
- clear
- InChI
- InChI=1S/C3H5FO/c4-1-3-2-5-3/h3H,1-2H2
- InChIKey
- OIFAHDAXIUURLN-UHFFFAOYSA-N
- SMILES
- O1CC1CF
- CAS Datenbank
- 503 · 503-09-3(CAS DataBase Reference)
- NIST chemische Informationen
- Oxirane, (fluoromethyl)-(503-09-3)
- EPA chemische Informationen
- Epifluorohydrin (503-09-3)
Sicherheit und Regulatorisches
GHS-Klassifizierung
GHS Classification
Danger
H225 (100%): Highly Flammable liquid and vapor [Danger Flammable liquids]
P210, P233, P240, P241, P242, P243, P260, P261, P262, P264, P270, P271, P280, P301+P316, P301+P330+P331, P302+P352, P302+P361+P354, P303+P361+P353, P304+P340, P305+P354+P338, P316, P321, P330, P361+P364, P363, P370+P378, P403+P233, P403+P235, P405, and P501 (click each P-code to see the statement)
Aggregated GHS information provided per 44 reports by companies from 4 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.
Gefahrenhinweise
Reactivity Profile
A halogenated epoxide. Epoxides are highly reactive. They polymerize in the presence of catalysts or when heated. These polymerization reactions can be violent. Compounds in this group react with acids, bases, and oxidizing and reducing agents. They react, possibly violently with water in the presence of acid and other catalysts. The chlorinated derivative has been shown to be incompatible with aniline, strong oxidizers, sulfuric acid, isopropylamine, zinc, aluminum, iron, etc. see epichlorohydrin.
Sicherheit und Schutzausrüstung
First Aid
EYES: First check the victim for contact lenses and remove if present. Flush victim's eyes with water or normal saline solution for 20 to 30 minutes while simultaneously calling a hospital or poison control center. Do not put any ointments, oils, or medication in the victim's eyes without specific instructions from a physician. IMMEDIATELY transport the victim after flushing eyes to a hospital even if no symptoms (such as redness or irritation) develop.
Nonfire Spill Response
SMALL SPILLS AND LEAKAGE: If you spill this chemical, FIRST REMOVE ALL SOURCES OF IGNITION. Then, use absorbent paper to pick up all liquid spill material. Seal the absorbent paper, as well as any of your clothing which may be contaminated, in a vapor-tight plastic bag for eventual disposal. Wash any surfaces you may have contaminated with a soap and water solution. Do not reenter the contaminated area until the Safety Officer (or other responsible person) has verified that the area has been properly cleaned.
Personal Protective Equipment (PPE)
RECOMMENDED RESPIRATOR: When working with this chemical, wear a NIOSH-approved full face chemical cartridge respirator equipped with the appropriate organic vapor cartridges. If that is not available, a half face respirator similarly equipped plus airtight goggles can be substituted. However, please note that half face respirators provide a substantially lower level of protection than do full face respirators. (NTP, 1992)
Sicherheitsdaten
- wgk
- 3
- ridadr
- UN 2924 3/PG 2
- hs_code
- 2910900090
- RTECS-Nr.
- TZ3325000
- risk_code
- 11-23/24/25-34
- hazard_code
- F,T
- hazard_note
- Flammable/Highly Toxic
- safety_code
- 16-26-45-38-36/37/39-33
- hazard_class
- 6.1(a)
- packing_group
- I
- Speicherklasse
- 3 - Flammable liquids
- Hazard Classifications
- Acute Tox. 3 DermalAcute Tox. 3 InhalationAcute Tox. 3 OralFlam. Liq. 2Skin Corr. 1B
Chemie und Industrie
Anwendungen
VerwendenEpifluorohydrin is used as a reagent in the synthesis of N-arylphosphoramidates. In addition, it is used in the synthesis of orally bioavailable ALK inhibitors in the treatment of tumors.
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