4-Hydroxybenzoic Acid → 4-Hydroxy-3-iodobenzoic acid (2IPCOOH)

HRID 133705

Reaktionsgleichung

Reaktionsgleichung von HRID 133705
[OH:1][C:2]1[CH:10]=[CH:9][C:5]([C:6]([OH:8])=[O:7])=[CH:4][CH:3]=1.[OH-].[Na+].[I-:13].[Na+].Cl[O-].[Na+].OS(O)(=O)=O>O>[OH:1][C:2]1[CH:10]=[CH:9][C:5]([C:6]([OH:8])=[O:7])=[CH:4][C:3]=1[I:13]

Komponenten

7

Edukt 5

HCID 1354-Hydroxybenzoic AcidHCID 1118Sulfuric AcidHCID 5238Sodium IodideHCID 14798Sodium HydroxideHCID 23665760Sodium Hypochlorite

Produkt 1

HCID 4494734-Hydroxy-3-iodobenzoic acid (2IPCOOH)

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 962WaterLösungsmittel

Versuchsvorschrift

30 g of 4-hydroxybenzoic acid are placed in 780 ml of water containing 18 g of sodium hydroxide, 49.5 g of sodium iodide are added, 675 ml of 3.5% sodium hypochlorite solution are run in slowly and the mixture is left with stirring at AT for 13 hours. 60 ml of concentrated H2SO4 are added and then, after cooling, the precipitate formed is filtered off and washed with water. This gives 32.46 g of the expected compound, m.p.=163° C.

Aufarbeitung

  1. additionare added
  2. waitis left
  3. temperatureafter cooling
  4. customthe precipitate formed
  5. filtrationis filtered off
  6. washwashed with water

Quellen und Nachweise

ORD-Eintrag
ord-f4bd56211cd14a3fb5d2d390152a6732
Quelldatensatz
uspto-grants-2008_06
Patentnummer
US07390924B2

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