Water → 4-[1-Carboxy-2-(4-fluoro-phenyl)-ethyl]-4-hydroxy-piperidine-1-carboxylic acid tert-butyl ester
Reaktionsgleichung
[C:25](=[O:26])([O:27][C:28]([CH3:29])([CH3:30])[CH3:31])[N:32]1[CH2:33][CH2:34][C:35](=[O:38])[CH2:36][CH2:37]1.[CH2:1]([Li:2])[CH2:3][CH2:4][CH3:5].[CH2:39]1[O:40][CH2:41][CH2:42][CH2:43]1.[CH2:45]([O:46][CH2:47][CH3:48])[CH3:49].[CH:6]([NH:7][CH:8]([CH3:9])[CH3:10])([CH3:11])[CH3:12].[F:13][c:14]1[cH:15][cH:16][c:17]([CH2:20][CH2:21][C:22](=[O:23])[OH:24])[cH:18][cH:19]1.[OH2:44]>>[F:13][c:14]1[cH:15][cH:16][c:17]([CH2:20][CH:21]([C:22](=[O:23])[OH:24])[C:35]2([OH:38])[CH2:34][CH2:33][N:32]([C:25](=[O:26])[O:27][C:28]([CH3:29])([CH3:30])[CH3:31])[CH2:37][CH2:36]2)[cH:18][cH:19]1
