Chlorobenzene → Benzoic Acid

HRID 1613962

Reaktionsgleichung

Reaktionsgleichung von HRID 1613962
Cl[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.C1(P(C(C(P(C2C=CC=CC=2)C2C=CC=CC=2)C)C)C2C=CC=CC=2)C=CC=CC=1.[C:38](=O)([O-:40])[O-:39].[K+].[K+].[C]=O>[Pd](Cl)Cl.O>[C:38]([OH:40])(=[O:39])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1

Komponenten

7

Edukt 4

HCID 7964ChlorobenzeneHCID 11430Potassium CarbonateHCID 3882352ChiraphosHCID 178418416HCID 178418416, Verbindung2×

Produkt 1

HCID 243Benzoic Acid

Reagenzien, Katalysatoren, Lösungsmittel 2

HCID 24290Palladium ChlorideKatalysatorHCID 962WaterLösungsmittel

Reaktionsbedingungen

Temperatur
210 °C

Versuchsvorschrift

In an autoclave made of metal were placed 11.2 g of chlorobenzene, 17.5 mg of palladium chloride, 427 mg of bisdiphenylphosphinobutane and 3.1 g of potassium carbonate. The air in the autoclave was replaced with carbon monoxide introduced thereinto in several times, after which carbon monoxide was further introduced to its pressure therein to 50 kg/cm2. The reaction was carried out with stirring for 3 hours on a salt bath at a bath temperature of 210° C. After completion of the reaction, the reaction mixture was cooled to room temperature and water was added. The aqueous layer was separated, after which acid was added thereto and the deposited crystals were collected by

Aufarbeitung

  1. additionintroduced
  2. customAfter completion of the reaction
  3. temperaturethe reaction mixture was cooled to room temperature
  4. customThe aqueous layer was separated
  5. additionafter which acid was added
  6. customthe deposited crystals were collected by

Quellen und Nachweise

ORD-Eintrag
ord-095b683e6d924901b542fa981debd102
Quelldatensatz
uspto-grants-1993_03
Patentnummer
US05194631

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