Water → 6-Butyl-benzothiazol-2-ylamine

HRID 538890Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 538890
[CH2:1]([C:5]1[CH:11]=[CH:10][C:8]([NH2:9])=[CH:7][CH:6]=1)[CH2:2][CH2:3][CH3:4].[C:12]([S-:14])#[N:13].[K+].BrBr.O>C(O)(=O)C>[CH2:1]([C:5]1[CH:6]=[CH:7][C:8]2[N:9]=[C:12]([NH2:13])[S:14][C:10]=2[CH:11]=1)[CH2:2][CH2:3][CH3:4]

Komponenten

6

Edukt 4

HCID 962WaterHCID 76944-ButylanilineHCID 24408BromineHCID 516872Potassium thiocyanate

Produkt 1

HCID 15892106-Butyl-benzothiazol-2-ylamine

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 176Acetic AcidLösungsmittel2×

Versuchsvorschrift

Step-1: To a mixture of 4-butylaniline 67 mmol) and KSCN (26 g, 268 mmol) in acetic acid was added Br2 in acetic acid (70 mL) dropwise over 6 min at RT. The mixture was stirred at RT overnight and poured into water (2 L). The precipitate was collected, washed with water and dried to afford 6-butylbenzo[d]thiazol-2-amine. MS (ESI+) m/z 207.20 [M+H]+

Aufarbeitung

  1. customThe precipitate was collected
  2. washwashed with water
  3. customdried

Quellen und Nachweise

ORD-Eintrag
ord-2f3844f8b86640e18bac4e2d12282a14
Quelldatensatz
uspto-grants-2014_10
Patentnummer
US08865752B2

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