Citric Acid → 2-Methyl-benzaldoxime

HRID 975237

Reaktionsgleichung

Reaktionsgleichung von HRID 975237
[CH3:1][C:2]1[CH:9]=[CH:8][CH:7]=[CH:6][C:3]=1[CH:4]=O.[Cl-].[OH:11][NH3+:12].[OH-].[Na+].C(O)(=O)CC(CC(O)=O)(C(O)=O)O>O.C(O)C>[CH3:1][C:2]1[CH:9]=[CH:8][CH:7]=[CH:6][C:3]=1[CH:4]=[N:12][OH:11]

Komponenten

7

Edukt 4

HCID 311Citric AcidHCID 107222-MethylbenzaldehydeHCID 14798Sodium HydroxideHCID 21645Hydroxylamine HCl

Produkt 1

HCID 1024012-Methyl-benzaldoximeAusbeute 70,7 %

Reagenzien, Katalysatoren, Lösungsmittel 2

HCID 702EthanolLösungsmittelHCID 962WaterLösungsmittel2×

Versuchsvorschrift

A mixture of 2-methylbenzaldehyde (10.8 g, 90 mmol), hydroxylammonium chloride (9.4 g, 135 mmol), sodium hydroxide (18.0,0.45 mol), ethanol (80 ml) and water (20 ml) was heated at reflux for 1 h. A solution of citric acid (20 g) in water (700 ml) was added and the mixture was left for crystallisation. The precipitate was collected and recrystallised from water to give 8.6 g of 2-methylbenzaldehyde oxime. M.p. 49.0-49.4° C.

Aufarbeitung

  1. temperaturewas heated
  2. temperatureat reflux for 1 h
  3. waitthe mixture was left for crystallisation
  4. customThe precipitate was collected
  5. customrecrystallised from water

Quellen und Nachweise

ORD-Eintrag
ord-4069212b558c4bb4a2e7772af3b8b12c
Quelldatensatz
uspto-grants-1997_03
Patentnummer
US05608069

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