1,2-Dichloroethane → Ethyl 4-(4-phenylbenzoyl)-1-piperidinecarboxylate

Reaction equation

[Al+3:14].[Cl-:13].[Cl-:15].[Cl-:16].[Cl:17][C:18](=[O:19])[CH:20]1[CH2:21][CH2:22][N:23]([C:26](=[O:27])[O:28][CH2:29][CH3:30])[CH2:24][CH2:25]1.[Cl:32][CH2:33][CH2:34][Cl:35].[ClH:31].[c:1]1(-[c:7]2[cH:8][cH:9][cH:10][cH:11][cH:12]2)[cH:2][cH:3][cH:4][cH:5][cH:6]1>>[c:1]1(-[c:7]2[cH:8][cH:9][c:10]([C:18](=[O:19])[CH:20]3[CH2:21][CH2:22][N:23]([C:26](=[O:27])[O:28][CH2:29][CH3:30])[CH2:24][CH2:25]3)[cH:11][cH:12]2)[cH:2][cH:3][cH:4][cH:5][cH:6]1

Participants

Reactant 6

HCID 111,2-Dichloroethane

HCID 312Chloride3×

HCID 313Hydrochloric Acid

HCID 7095Biphenyl

HCID 104727Aluminum Cation

HCID 11096122Ethyl 4-(chlorocarbonyl)-1-piperidinecarboxylate

Product 1

HCID 18432031Ethyl 4-(4-phenylbenzoyl)-1-piperidinecarboxylate

Sources & evidence

ORD record: ord-85c4f21520ee4e36869073ba6832535b
Source dataset: Training data from https://doi.org/10.1039/C8SC04228D (2/10)
DOI: 10.1039/C8SC04228D

Reaction notes

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